{"product_id":"copy-of-zoetis-inforce-3-respiratory-vaccine","title":"Zoetis INFORCE 3® Respiratory Vaccine","description":"\u003cdiv class=\"pdp-hero__content mb-4 pb-2 d-none d-md-block\"\u003e\n\u003cdiv class=\"pdp-hero__content mb-4 pb-2 d-none d-md-block\"\u003e\n\u003cp\u003eRespiratory disease can challenge young calves and dairy cows immediately before and at calving. INFORCE 3® the market-leading cattle respiratory vaccine\u003csup\u003e1\u003c\/sup\u003e, is for the vaccination of healthy cattle, including pregnant cows, to help protect against respiratory disease caused by bovine respiratory syncytial virus (BRSV), infectious bovine rhinotracheitis (IBR) virus and parainfluenza3 (PI3) virus. For dairy herds, INFORCE 3 can be used in calves as young as 3 days old, at weaning, before moving to group pens, or with cows and heifers at prefreshening.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pdp-hero__indication d-none d-md-block\"\u003e\n\u003ch6 class=\"pdp-hero__indication-header d-none d-md-block\"\u003eIndications\u003c\/h6\u003e\nHelps protect against respiratory disease caused by BRSV, IBR and PI\u003csub\u003e3\u003c\/sub\u003e.\u003c\/div\u003e\n\u003cdiv class=\"pdp-hero__options pt-3 mt-3 row\"\u003e\n\u003cdiv class=\"pdp-hero__options col-lg-6\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv class=\"pdp-hero__options-available col-6\" id=\"avail\"\u003e\n\u003ch6 class=\"mb-2 pdp-hero__options-available-header\"\u003eAvailable As\u003c\/h6\u003e\n\u003cp class=\"pdp-hero__options-items\"\u003eVials\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pdp-hero__options-use col-6\" id=\"use\"\u003e\n\u003ch6 class=\"mb-2 pdp-hero__options-use-header\"\u003eFor use with\u003c\/h6\u003e\n\u003cp class=\"pdp-hero__options-items\"\u003eBeef\u003c\/p\u003e\n\u003cp class=\"pdp-hero__options-items\"\u003eDairy\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pdp-hero__options pt-3 mt-3 row\"\u003e\n\u003cdiv class=\"pdp-hero__options col-lg-6\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv id=\"use\" class=\"pdp-hero__options-use col-6\"\u003e\n\u003cdiv\u003e\n\u003cdiv id=\"product-support\" class=\"product-support-section\"\u003e\n\u003cdiv class=\"references\"\u003e\n\u003cdiv class=\"references__body\"\u003e\n\u003ch2 class=\"section-header__title\"\u003eHow it Works\u003c\/h2\u003e\n\u003cdiv class=\"section-header__body wysiwyg\"\u003e\n\u003cp\u003eAs an intranasal respiratory vaccine, INFORCE 3\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003ecauses a local immune response with viral antibodies produced in the nasal passage where BRSV, IBR and PI\u003csub\u003e3\u003c\/sub\u003e\u003cspan\u003e \u003c\/span\u003eare most likely to enter the animal’s system.\u003c\/p\u003e\n\u003cp\u003eINFORCE 3\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eis the first commercially-available intranasal respiratory vaccine to help protect against respiratory disease caused by BRSV, while also protecting against IBR and PI\u003csub\u003e3\u003c\/sub\u003e, to help get cattle off to a healthier, more productive start.\u003c\/p\u003e\n\u003cp\u003eINFORCE 3 has a six-month duration of immunity claim for IBR protection, and a single-nostril administration claim. Additional research also demonstrated no maternal antibody interference for IBR and BRSV.\u003csup\u003e2,3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cb\u003eSafe for all ages, types and classes of cattle\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eINFORCE 3\u003csup\u003e®\u003c\/sup\u003e\u003cspan\u003e \u003c\/span\u003eis safe for use in all types, ages and classes of cattle. INFORCE 3 was demonstrated safe for use in very young, high-stress calves; weaned and high-stress stocker calves; and pregnant heifers and cows.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eThe Science Behind Effective Control\u003c\/b\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003eIntranasal administration works with the animal's immune system for fast, effective response\u003c\/li\u003e\n\u003cli\u003eHelps prime the immune system for a memory response to subsequent vaccinations as well as disease challenges\u003c\/li\u003e\n\u003cli\u003eContains proprietary, temperature-sensitive IBR and PI\u003csub\u003e3\u003c\/sub\u003e strains that replicate most effectively in the upper respiratory tract\u003c\/li\u003e\n\u003cli\u003eStimulates interferon release for protection\u003c\/li\u003e\n\u003cli\u003eHelps deliver a healthy start for young dairy calves\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eProven Respiratory Disease Protection\u003c\/b\u003e\u003c\/p\u003e\n\u003cul type=\"disc\"\u003e\n\u003cli\u003eIn two different studies, all calves vaccinated with INFORCE 3 survived severe BRSV challenges in which 100% and 90% of unvaccinated controls either died or had to be humanely euthanized.\u003csup\u003e4,5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eINFORCE 3 was shown to help prevent respiratory disease caused by IBR and PI\u003csub\u003e3\u003c\/sub\u003e\u003cspan\u003e \u003c\/span\u003eand reduce level and duration of viral shedding caused by IBR and PI\u003csub\u003e3\u003c\/sub\u003e.\u003csup\u003e6-8\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eA study comparing INFORCE 3 and TSV-2\u003csup\u003e®\u003c\/sup\u003e demonstrated that vaccinating cows and heifers with INFORCE 3  prior to freshening helped support overall positive production:\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003e205 pounds more milk per cow per lactation\u003csup\u003e9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eIncreased income per cow\u003csup\u003e9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cb\u003eDirections\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eAseptically rehydrate the freeze-dried vaccine with the sterile diluent provided, mix well and administer 2 mL intranasally using a cannula. Place the 2-mL dose in a single nostril or place 1-mL in each nostril. \u003c\/p\u003e\n\u003cp\u003eCalves vaccinated before the age of 6 months should be revaccinated after 6 months of age to avoid possible maternal antibody interference with immunization. Annual revaccination with a single dose is recommended. \u003c\/p\u003e\n\u003cp\u003eFor further advice on revaccination frequency, consult your veterinarian.\u003c\/p\u003e\n\u003ch4\u003ePRECAUTIONS:\u003c\/h4\u003e\n\u003col\u003e\n\u003cli\u003e\n\u003cp\u003eStore at 2°-8°C. Prolonged exposure to higher temperatures and\/or direct sunlight may adversely affect potency. Do not freeze.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eUse entire contents when first opened.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eSterilized syringes should be used to administer this vaccine. Do not sterilize with chemicals because traces of disinfectant may inactivate the vaccine.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eInactivate unused contents before disposal.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eDo not vaccinate within 21 days before slaughter.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eContains gentamicin as preservative.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eFetal health risks associated with the vaccination of pregnant animals with modified live vaccines cannot be unequivocally determined during clinical trials conducted for licensure. Appropriate strategies to address the risks associated with modified live vaccine use in pregnant animals should be discussed with a veterinarian.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp\u003eAs with many vaccines, anaphylaxis may occur after use. Initial antidote of epinephrine is recommended and should be followed with appropriate supportive therapy.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cblockquote\u003e\n\u003ch3 class=\"references__header\"\u003eReferences\u003c\/h3\u003e\n\u003cdiv class=\"references__body\"\u003e\n\u003col\u003e\n\u003cli\u003eBased on number of doses and overall sales of respiratory vaccines. Animalytics Segment Data, Biologicals Therapeutic Category, Ending MAT May 2021.\u003c\/li\u003e\n\u003cli\u003eMahan SM, Sobecki B, Johnson J, et al. Efficacy of Intranasal Vaccination With a Multivalent Vaccine Containing Temperature-Sensitive Modified-Live Bovine Herpesvirus Type 1 for Protection of Seronegative and Seropositive Calves Against Respiratory Disease\u003cem\u003e. J Am Vet Med Assoc\u003c\/em\u003e. 2016;248(11):1280-1286.\u003c\/li\u003e\n\u003cli\u003eEllis JA, Gow SP, Mahan S, Leyh R. Duration of Immunity to Experimental Infection With Bovine Respiratory Syncytial Virus Following Intranasal Vaccination of Young Passively Immune Calves.\u003cspan\u003e \u003c\/span\u003e\u003cem\u003eJ Am Vet Med Assoc\u003c\/em\u003e. 2013;243(11):1602-1608.\u003c\/li\u003e\n\u003cli\u003eData on file, Study Report No. 3131R-60-08-557, Zoetis Inc.\u003c\/li\u003e\n\u003cli\u003eData on file, Study Report No. 3131R-60-09-669, Zoetis Inc.\u003c\/li\u003e\n\u003cli\u003eData on file, Study Report No. 3131R-60-08-548, Zoetis Inc.\u003c\/li\u003e\n\u003cli\u003eData on file, Study Report No. 3131R-60-09-720, Zoetis Inc.\u003c\/li\u003e\n\u003cli\u003eData on file, Study Report No. 3131R-60-08-568, Zoetis Inc.\u003c\/li\u003e\n\u003cli\u003eData on file, Study Report No. 10PETINF01, Zoetis Inc.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003c\/blockquote\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"pdp-hero__options pt-3 mt-3 row\"\u003e\n\u003cdiv class=\"pdp-hero__options col-lg-6\"\u003e\n\u003cdiv class=\"row\"\u003e\n\u003cdiv id=\"use\" class=\"pdp-hero__options-use col-6\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"ZOETIS","offers":[{"title":"10 Dose","offer_id":46813473996975,"sku":"11402621","price":21.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0734\/6415\/2239\/files\/product-media-336486.jpg?v=1777379012","url":"https:\/\/freshized.com\/products\/copy-of-zoetis-inforce-3-respiratory-vaccine","provider":"Freshized","version":"1.0","type":"link"}